Download Adenosine Receptors in Neurology and Psychiatry, by Akihisa Mori PDF

By Akihisa Mori

This well-established overseas sequence examines significant components of uncomplicated and medical examine inside of neuroscience, in addition to rising and promising subfields. This quantity concentrates on adenosine receptor technological know-how, offering insights precious for real drug discovery/development in neurology and psychiatry areas.

  • Expertise of contributors
  • Subject together with functional drug improvement from simple technology, as translational learn taste
  • Structure of contents targeting CNS components for illnesses (neurology and psychiatry)

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Additional resources for Adenosine Receptors in Neurology and Psychiatry,

Example text

Neuroprotection by adenosine A2A receptor blockade in experimental models of Parkinson’s disease. Journal of Neurochemistry, 80, 262–270. Adenosine Receptor Neurobiology: Overview 39 Iliff, J. , Ngai, A. , & Winn, H. R. (2003). Adenosine receptors mediate glutamate-evoked arteriolar dilation in the rat cerebral cortex. American Journal of Physiology. Heart and Circulatory Physiology, 284, H1631–H1637. Ivanov, A. , & Jacobson, K. A. (2009). Evaluation of homology modeling of G-protein-coupled receptors in light of the A(2A) adenosine receptor crystallographic structure.

Sandilos, J. , Walk, S. , Kinchen, J. , Lazarowski, E. , et al. (2010). Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis. Nature, 467, 863–867. , et al. (2006). ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science, 314, 1792–1795. Chen, J. , Eltzschig, H. , & Fredholm, B. B. (2013). Adenosine receptors as drug targets—What are the challenges? Nature Reviews Drug Discovery, 12, 265–286. , Gawryluk, J. , Wagener, J. , & Geiger, J.

Matharu, A. , Mundell, S. , Benovic, J. , & Kelly, E. (2001). Rapid agonist-induced desensitization and internalization of the A(2B) adenosine receptor is mediated by a serine residue close to the COOH terminus. The Journal of Biological Chemistry, 276, 30199–30207. , Cunha, R. , & Chen, J. F. (2013). Antagonistic interaction between adenosine A2A receptors and Na +/K+-ATPase-alpha2 controlling glutamate uptake in astrocytes. The Journal of Neuroscience, 33, 18492–18502. , Santos-Rodrigues, A. , Schwarzschild, M.

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